Reply to: “Re-evaluating the evidence for a universal genetic boundary among microbial species”
Rodriguez-R LM, Jain C, Conrad RE, Aluru S, Konstantinidis KT.
Nat Comm, 2021.
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A debate on the existence of a natural genetic discontinuity between prokaryotic species:
- Jain et al, 2018: High throughput ANI analysis of 90K prokaryotic genomes reveals clear species boundaries.
- Murray et al, 2021: Re-evaluating the evidence for a universal genetic boundary among microbial species.
- Rodriguez-R et al, 2021: Reply to: “Re-evaluating the evidence for a universal genetic boundary among microbial species”
In this paper, we provide a detailed point-by-point response to the concerns raised by Murray and collaborators.